| # | Team | MP | W | D | L | F | A | G | P |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Zenit | 26 | 16 | 7 | 3 | 59 | 24 | +35 | 55 |
| 2 | Lokomotiv Moscow | 26 | 15 | 4 | 7 | 38 | 27 | +11 | 49 |
| 3 | Spartak Moscow | 26 | 14 | 5 | 7 | 49 | 33 | +16 | 47 |
| 4 | Rubin Kazan | 26 | 14 | 4 | 8 | 35 | 29 | +6 | 46 |
| 5 | CSKA Moscow | 26 | 14 | 4 | 8 | 45 | 27 | +18 | 46 |
| 6 | Dinamo Moscow | 26 | 14 | 4 | 8 | 41 | 28 | +13 | 46 |
| 7 | Sochi | 26 | 12 | 7 | 7 | 41 | 29 | +12 | 43 |
| 8 | Khimki | 26 | 11 | 5 | 10 | 32 | 37 | -5 | 38 |
| 9 | Rostov | 26 | 11 | 4 | 11 | 33 | 31 | +2 | 37 |
| 10 | Akhmat Grozny | 26 | 10 | 5 | 11 | 30 | 33 | -3 | 35 |
| 11 | Krasnodar | 26 | 10 | 5 | 11 | 46 | 38 | +8 | 35 |
| 12 | Ural | 26 | 6 | 12 | 8 | 24 | 33 | -9 | 30 |
| 13 | Arsenal Tula | 26 | 6 | 5 | 15 | 24 | 42 | -18 | 23 |
| 14 | Ufa | 26 | 5 | 5 | 16 | 21 | 41 | -20 | 20 |
| 15 | Rotor Volgograd | 26 | 4 | 6 | 16 | 12 | 43 | -31 | 18 |
| 16 | Tambov | 26 | 3 | 4 | 19 | 15 | 50 | -35 | 13 |
Результаты
| Sunday, April 18, 2021 | ||
| Spartak Moscow | 0 - 3 | Ufa |
| Sochi | 2 - 1 | CSKA Moscow |
| Arsenal Tula | 4 - 0 | Tambov |
| Ural | 0 - 1 | Rubin Kazan |
| Saturday, April 17, 2021 | ||
| Krasnodar | 2 - 2 | Zenit |
| Rotor Volgograd | 0 - 3 | Dinamo Moscow |
| Lokomotiv Moscow | 4 - 1 | Rostov |
| Akhmat Grozny | 3 - 1 | Khimki |
| Monday, April 12, 2021 | ||
| CSKA Moscow | 2 - 0 | Rotor Volgograd |
| Sunday, April 11, 2021 | ||
| Lokomotiv Moscow | 2 - 0 | Spartak Moscow |
Следующий тур
| Saturday, April 24, 2021 | ||
| Ural | 11:00 | Akhmat Grozny |
| Zenit | 13:30 | Rotor Volgograd |
| Dinamo Moscow | 16:00 | Khimki |
| Tambov | 16:00 | Lokomotiv Moscow |
| Sunday, April 25, 2021 | ||
| Ufa | 11:00 | Sochi |
| Spartak Moscow | 13:30 | CSKA Moscow |
| Rostov | 13:30 | Arsenal Tula |
| Rubin Kazan | 16:00 | Krasnodar |
| Saturday, May 1, 2021 | ||
| Rubin Kazan | 11:00 | Dinamo Moscow |
| Rotor Volgograd | 11:00 | Akhmat Grozny |
