| # | Team | MP | W | D | L | F | A | G | P |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Benfica | 8 | 7 | 0 | 1 | 19 | 5 | +14 | 21 |
| 2 | Porto | 8 | 6 | 2 | 0 | 18 | 5 | +13 | 20 |
| 3 | Sporting Lisbon | 8 | 6 | 2 | 0 | 13 | 4 | +9 | 20 |
| 4 | Estoril | 8 | 4 | 3 | 1 | 12 | 7 | +5 | 15 |
| 5 | Portimonense | 8 | 4 | 2 | 2 | 8 | 4 | +4 | 14 |
| 6 | SC Braga | 8 | 3 | 4 | 1 | 12 | 8 | +4 | 13 |
| 7 | Vitoria Guimaraes | 8 | 2 | 4 | 2 | 9 | 7 | +2 | 10 |
| 8 | Boavista | 8 | 2 | 4 | 2 | 11 | 11 | +0 | 10 |
| 9 | Gil Vicente | 8 | 2 | 3 | 3 | 10 | 10 | +0 | 9 |
| 10 | Tondela | 8 | 3 | 0 | 5 | 12 | 14 | -2 | 9 |
| 11 | Paços Ferreira | 8 | 2 | 3 | 3 | 8 | 11 | -3 | 9 |
| 12 | Vizela | 8 | 1 | 5 | 2 | 7 | 13 | -6 | 8 |
| 13 | Marítimo | 8 | 1 | 4 | 3 | 6 | 9 | -3 | 7 |
| 14 | Moreirense | 8 | 1 | 4 | 3 | 10 | 16 | -6 | 7 |
| 15 | Santa Clara | 8 | 1 | 3 | 4 | 6 | 16 | -10 | 6 |
| 16 | Arouca | 8 | 1 | 2 | 5 | 8 | 16 | -8 | 5 |
| 17 | Belenenses | 8 | 0 | 4 | 4 | 5 | 12 | -7 | 4 |
| 18 | Famalicão | 8 | 0 | 3 | 5 | 8 | 14 | -6 | 3 |
Результаты
| Sunday, October 3, 2021 | ||
| SC Braga | 2 - 2 | Boavista |
| Estoril | 2 - 2 | Gil Vicente |
| Benfica | 0 - 1 | Portimonense |
| Belenenses | 0 - 2 | Tondela |
| Saturday, October 2, 2021 | ||
| Arouca | 1 - 2 | Sporting Lisbon |
| Porto | 2 - 1 | Paços Ferreira |
| Vizela | 1 - 1 | Santa Clara |
| Friday, October 1, 2021 | ||
| Famalicão | 1 - 2 | Vitoria Guimaraes |
| Marítimo | 0 - 0 | Moreirense |
| Monday, September 27, 2021 | ||
| Boavista | 1 - 1 | Estoril |
Следующий тур
| Friday, October 22, 2021 | ||
| Vitoria Guimaraes | 19:15 | Marítimo |
| Saturday, October 23, 2021 | ||
| Santa Clara | 14:30 | Famalicão |
| Tondela | 17:00 | Porto |
| Sporting Lisbon | 19:30 | Moreirense |
| Sunday, October 24, 2021 | ||
| Paços Ferreira | 14:30 | Arouca |
| Vizela | 17:00 | Benfica |
| Portimonense | 19:30 | Estoril |
| Monday, October 25, 2021 | ||
| Gil Vicente | 18:00 | SC Braga |
| Boavista | 20:15 | Belenenses |
| Friday, October 29, 2021 | ||
| Arouca | 19:15 | Tondela |
