| # | Team | MP | W | D | L | F | A | G | P |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Manchester City | 32 | 23 | 5 | 4 | 67 | 23 | +44 | 74 |
| 2 | Manchester United | 32 | 19 | 9 | 4 | 64 | 35 | +29 | 66 |
| 3 | Leicester City | 31 | 17 | 5 | 9 | 55 | 37 | +18 | 56 |
| 4 | Chelsea | 32 | 15 | 10 | 7 | 50 | 31 | +19 | 55 |
| 5 | West Ham United | 32 | 16 | 7 | 9 | 53 | 42 | +11 | 55 |
| 6 | Liverpool | 32 | 15 | 8 | 9 | 54 | 38 | +16 | 53 |
| 7 | Tottenham Hotspur | 32 | 14 | 8 | 10 | 54 | 37 | +17 | 50 |
| 8 | Everton | 31 | 14 | 7 | 10 | 43 | 40 | +3 | 49 |
| 9 | Arsenal | 32 | 13 | 7 | 12 | 44 | 36 | +8 | 46 |
| 10 | Leeds United | 32 | 14 | 4 | 14 | 50 | 50 | +0 | 46 |
| 11 | Aston Villa | 30 | 13 | 5 | 12 | 43 | 33 | +10 | 44 |
| 12 | Wolverhampton Wanderers | 32 | 11 | 8 | 13 | 32 | 41 | -9 | 41 |
| 13 | Crystal Palace | 31 | 10 | 8 | 13 | 33 | 52 | -19 | 38 |
| 14 | Southampton | 31 | 10 | 6 | 15 | 39 | 56 | -17 | 36 |
| 15 | Newcastle United | 32 | 9 | 8 | 15 | 35 | 53 | -18 | 35 |
| 16 | Brighton & Hov… | 32 | 7 | 13 | 12 | 33 | 38 | -5 | 34 |
| 17 | Burnley | 32 | 8 | 9 | 15 | 26 | 45 | -19 | 33 |
| 18 | Fulham | 33 | 5 | 12 | 16 | 25 | 43 | -18 | 27 |
| 19 | West Bromwich Albion | 31 | 5 | 9 | 17 | 28 | 59 | -31 | 24 |
| 20 | Sheffield United | 32 | 4 | 2 | 26 | 17 | 56 | -39 | 14 |
Результаты
| Tuesday, April 20, 2021 | ||
| Chelsea | 0 - 0 | Brighton & Hov… |
| Monday, April 19, 2021 | ||
| Leeds United | 1 - 1 | Liverpool |
| Sunday, April 18, 2021 | ||
| Manchester United | 3 - 1 | Burnley |
| Arsenal | 1 - 1 | Fulham |
| Saturday, April 17, 2021 | ||
| Wolverhampton Wanderers | 1 - 0 | Sheffield United |
| Newcastle United | 3 - 2 | West Ham United |
| Friday, April 16, 2021 | ||
| Everton | 2 - 2 | Tottenham Hotspur |
| Monday, April 12, 2021 | ||
| Brighton & Hov… | 0 - 0 | Everton |
| West Bromwich Albion | 3 - 0 | Southampton |
| Sunday, April 11, 2021 | ||
| Sheffield United | 0 - 3 | Arsenal |
Следующий тур
| Sunday, January 17, 2021 | ||
| Aston Villa | 01:00 | Everton |
| Saturday, April 17, 2021 | ||
| Southampton | 00:00 | Crystal Palace |
| Wednesday, April 21, 2021 | ||
| Tottenham Hotspur | 17:00 | Southampton |
| Aston Villa | 19:15 | Manchester City |
| Thursday, April 22, 2021 | ||
| Leicester City | 19:00 | West Bromwich Albion |
| Friday, April 23, 2021 | ||
| Arsenal | 19:00 | Everton |
| Saturday, April 24, 2021 | ||
| Liverpool | 11:30 | Newcastle United |
| West Ham United | 16:30 | Chelsea |
| Sheffield United | 19:00 | Brighton & Hov… |
| Sunday, April 25, 2021 | ||
| Wolverhampton Wanderers | 11:00 | Burnley |
